Dopacone 200/50/200mg (10 Tablet / Pack)

A premium triple-combination therapy engineered for precise motor symptom management in Parkinson's disease.

PKR 765.00

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SKU: DOPACONE_20050200MG_10_TABLET_PACK

Category: Tablets & Capsules

Dopacone Tablets contain a precise triple-combination therapy of Levodopa, Carbidopa, and Entacapone. Levodopa serves as a metabolic precursor that crosses the blood-brain barrier to replace depleted dopamine levels in the corpus striatum, while Carbidopa acts as a peripheral dopa-decarboxylase inhibitor to prevent the premature breakdown of Levodopa outside the brain. Entacapone functions as a selective, reversible inhibitor of catechol-O-methyltransferase (COMT), extending the therapeutic plasma half-life of Levodopa to significantly minimize 'wearing-off' motor fluctuations.

Purpose

Used for the treatment of patients with Parkinson's disease who experience end-of-dose motor fluctuations not adequately managed by standard levodopa/dopa decarboxylase inhibitor combinations.

Ingredients

Levodopa 200mg + Carbidopa 50mg + Entacapone 200mg

Warnings

Do not discontinue or reduce the dosage abruptly to avoid the risk of precipitating Neuroleptic Malignant Syndrome (NMS) or acute hyperpyrexia.

May cause severe orthostatic hypotension and somnolence; exercise extreme caution when driving or operating machinery.

Inform patients that this medication can safely cause a harmless, brownish-orange discoloration of urine, sweat, and saliva.

Closely monitor patients for the emergence of intense gambling urges, increased libido, or other compulsive impulse control disorders.

Side Effects

Pervasive involuntary movements (dyskinesia), muscle cramps, or generalized physical tremors.

Gastrointestinal disturbances including nausea, vomiting, abdominal pain, diarrhea, or severe dryness of the mouth.

Central nervous system effects such as dizziness, vivid dreams, insomnia, confusion, or hallucinations.

Harmless darkening or reddish-brown discoloration of bodily fluids including urine and sweat.